Scheme 1. Synthesis of 1,2,4-Triazin-5(4H)-ones.
Reaction conditions: (i) 2-propanol, 40 °C, then r.t., 2 d; (ii) ethyl 2-amino-2-thioxoacetate, 75 °C, 2.5 h, then ice water, 16 h.
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