Scheme 3. Scope of Cyclopropane Formation via HB Alkylation of Ketone Substrate 7.
Reactions were performed on a 0.30–0.60 mmol scale unless otherwise stated. Isolated yields are reported.
KOH (2 equiv) and tBuOH added after 24 h; reaction heated for a further 24 h.
Reaction was performed on a 1.00 mmol scale.
Reaction performed at 90 °C.