Table 1. Optimization of the Aryloxy Leaving Group and Ketone Protecting Group.

Reactions were performed on 0.30 mmol scale. Isolated yields are shown.

^aKOH (2 equiv) and ^tBuOH were added after 24 h and the reaction heated for a further 24 h.

^bRu-MACHO (2 mol %) was used instead of [Ir(cod)Cl]₂ and dppBz.