TABLE 1.
Statistics of simulated total activation time 95% (TAT95), QRSd, the ML-score and distance from LV pacing site to the scar area at baseline LBBB activation and BiV pacing at ref-PS and ML-PS in the total patient cohort and groups of responders and non-responders.
| Simulated feature | Total cohort (n = 57) | Responders (n = 23) | Non-responders (n = 34) | |
|---|---|---|---|---|
| TAT95, ms | LBBB | 151 [137; 166] | 153 [141; 164] | 150 [133; 169] |
| ref-PS | 99 [88; 111]* | 96 [88; 106]* | 102 [88; 112]* | |
| ML-PS | 100 [89; 114]* | 99 [89; 113]* | 102 [86; 114]* | |
| QRSd, ms | LBBB | 190 [175; 205] | 195 [180; 204] | 189 [173; 210] |
| ref-PS | 142 [132; 155]* | 142 [132; 151]* | 147 [131; 156]* | |
| ML-PS | 144 [132; 154]* | 142 [136; 152]* | 144 [129; 157]* | |
| ML-score | ref-PS | 0.31 [0.14; 0.68] | 0.73 [0.36; 0.95] | 0.19 [0.07; 0.39]# |
| ML-PS | 0.56 [0.33; 0.87]$ | 0.82 [0.64; 0.98]$ | 0.42 [0.20; 0.73]$, # | |
| Scar-LVPS distance, mm | ref-PS | 34 [10; 49] | 44 [19; 53] | 25 [3; 43]# |
| ML-PS | 58 [45; 71]$ | 61 [51; 66]$ | 55 [41; 72]$ | |
| D PS , mm | ML-PS | 50 [26; 78] | 35 [21; 61] | 64 [41; 92]# |
Median [25th percentile; 75th percentile]. * - p 0.05, * - p 0.01 ML-PS vs. LBBB. $ - p 0.05, $ - p 0.01 ML-PS vs. ref-PS. Comparison of dependent groups was performed using Friedman’s test, followed by a pairwise comparison adjusted for multiple comparisons. # - p 0.05, # - p 0.01 Responders vs. Non-responders. Comparison between two independent groups was carried out using Mann-Whitney test.