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A) 24 hour time course for DcpS degradation by 1 μM JCS-1 in MOLM-14 cells. B) DcpS recovery following washout after 24 hour initial treatment with 1 μM JCS-1 with or without 10 μM VHL-ligand to compete against residual PROTAC action following washout. Quantified data represents the mean ± SD from three independent biological replicates. One-way ANOVA, * p < 0.05, **** p < 0.001
