TABLE 1.
Baseline characteristics of children and women (n = 775) enrolled in studies in 6 countries1
| Burkina Faso | Cameroon | Ethiopia | South Africa | Tanzania | Zambia 2010 | Zambia 2012 | Zambia 2019 |
||
|---|---|---|---|---|---|---|---|---|---|
| Nonlactating | Lactating | ||||||||
| n | 104 | 45 | 130 | 93 | 95 | 39 | 133 | 63 | 75 |
| Sex, female (%) | 46.2 | 53.3 | 44.6 | 54.8 | 47.4 | 46.2 | 45.1 | 100 | 100 |
| Age (mos) | 49.1 (42.8, 52.9) | 60.0 (48.0, 60.0) | 48.0 (41.0, 54.0) | 45.2 (39.2, 52.4) | 47.8 (41.2, 53.3) | 54.5 (46.0, 60.0) | 70.0 (66.0, 77.0) | 360 (276, 456) | 336 (270, 396) |
| Weight (kg) | 14.7 (13.6, 16.1) | 17.0 (15.0, 19.0) | 14.0 (12.7, 15.4) | 13.4 (12.2, 14.8) | 14.4 (13.4, 15.7) | 14.3 (13.3, 16.2) | 16.9 (15.8, 18.7) | 57.7 (51.1, 67.0) | 56.7 (52.0, 64.3) |
| Height (cm) | 98.1 (93.8, 102) | 107 (101, 111) | 96.5 (92, 103) | 94.9 (92.0, 98.2) | 96.3 (91.0, 100) | 98.8 (91.0, 103) | 107 (104, 112) | 157 (153, 161) | 157 (153, 164) |
| Retinol (μmol/L)2 | 0.833 (0.668, 0.959) | 0.787 (0.679, 0.932) | 0.778 (0.635, 0.941) | 1.07 (0.890, 1.29) | 1.04 (0.845, 1.22) | — | 0.959 (0.762, 1.17) | 1.64 (1.33, 2.09) | 1.55 (1.31, 1.94) |
| RBP (μmol/L)2 | 0.818 (0.675, 1.09) | 0.875 (0.665, 0.990) | 0.860 (0.685, 1.03) | 0.935 (0.745, 1.24) | 0.805 (0.667, 1.01) | — | 0.93 (0.697, 1.35) | — | — |
| CRP (mg/L)2 | 0.120 (0.010, 1.012) | 3.07 (0.535, 16.2) | 0.230 (0.010, 0.930) | 0.140 (0.010, 0.890) | 0.235 (0.010, 1.250) | 1.37 (0.773, 2.43) | 1.36 (0.433, 7.02) | — | — |
| AGP (g/L)2 | 0.705 (0.538, 1.12) | 1.12 (0.675, 1.48) | 0.705 (0.550, 1.19) | 0.630 (0.445, 0.915) | 0.645 (0.460, 0.915) | 1.12 (0.861, 1.64) | 2.39 (1.956, 2.88) | — | — |
| TBS (μmol) | 431 (290, 613) | 644 (519, 922) | 105 (60, 154) | 561 (418, 678) | 217 (147, 307) | — | 700 (536, 852) | 451 (319, 609) | 285 (209, 459) |
| TLR (50%)3 | 0.489 (0.339, 0.742) | 0.632 (0.538, 0.853) | 0.121 (0.072, 0.176) | 0.684 (0.548, 0.863) | 0.251 (0.182, 0.350) | — | 0.652 (0.528, 0.845) | 0.165 (0.111, 0.213) | 0.102 (0.076, 0.160) |
| TLR (80%)4 | 0.783 (0.542, 1.187) | 1.01 (0.861, 1.37) | 0.193 (0.115, 0.282) | 1.10 (0.877, 1.381) | 0.401 (0.291, 0.560) | — | 1.04 (0.845, 1.35) | 0.264 (0.178, 0.341) | 0.163 (0.121, 0.255) |
AGP, α-1-acid-glycoprotein; TLR, total liver vitamin A reserve; TBS, total body vitamin A store; —, not measured or data not available.
1
Data are % or median (Q1, Q3).
2
Analytes measured in serum.
3
Total liver reserves assuming 50% of total body vitamin A in liver.
4
Total liver reserves assuming 80% of total body vitamin A in liver.