TABLE 3.
Comparison of vitamin A total body stores and estimated liver concentrations using individual and population retinol 13C-natural abundance in children and women from 6 African countries
| TBS-study1 |
TBS-global1 |
TLR-study |
TLR-global |
TLR-study |
TLR-global |
|
|---|---|---|---|---|---|---|
| (μmol) | 50% of TBS in liver (μmol/g) | 80% of TBS in liver (μmol/g) | ||||
| Children | ||||||
| Mean bias | −17 | 14 | −0.018 | 0.011 | −0.029 | 0.017 |
| 95% LoA | (−318, 283) | (−370, 398) | (−0.343, 0.306) | (−0.390, 0.411) | (−0.549, 0.490) | (−0.623, 0.657) |
| Mean bias % of reference mean2 | −1.7 | 2.2 | −0.7 | 1.4 | −1.1 | 2.2 |
| 95% LoA | (−23, 20) | (−32, 37) | (−15, 13) | (−20, 23) | (−23, 21) | (−32, 37) |
| n | 570 | 568 | 568 | |||
| Women | ||||||
| Mean bias | −31 | −25 | −0.010 | −0.008 | −0.016 | −0.012 |
| 95% LoA | (−202, 139) | (−180, 130) | (−0.063, 0.043) | (−0.056, 0.041) | (−0.100, 0.069) | (−0.090, 0.066) |
| Mean bias % of reference mean2 | −3.7 | −2.5 | −2.3 | −1.6 | −3.7 | −2.5 |
| 95% LoA | (−21, 14) | (−20, 14) | (−13, 9) | (−12, 9) | (−21, 14) | (−20, 14) |
| n | 136 | 136 | 136 | |||
LoA, limits of agreement; TBS, total body vitamin A store; TLR, total liver vitamin A reserve.
Study and global refer to TBS or TLR outcomes calculated using study and global population-level retinol 13C-natural abundance values, respectively.
Mean bias, mean bias % of individual reference, and 95% limits of agreement were determined relative to vitamin A outcomes calculated using individual retinol 13C-natural abundance values within children or women subgroups.