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Immune Cell Patterns in CAVD. (A) Workflow of the scRNA-seq data analysis. (B) Pattern of immune cell infiltration in CAVD. (C) Correlation analysis between expression levels of SPP1, HMOX1, CD28 and immune cells. (D) The t-SNE projection cluster scatter diagram of the combined CAVD and health samples in PRJNA562645, with 6 identified cell types. (E) Volcano plot of DEGs in macrophages between CAVD and health. *p < 0.05; **p < 0.01; ****p < 0.0001
