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. 2023 Jul 25;24:419. doi: 10.1186/s12864-023-09441-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — CAVD-related DEGs between BAVs and TAVs, and different genders. (A) Workflow of the differential analysis. (B) Volcano plot of the DEGs between calcified cBAVs and cTAVs from GSE76718 and GSE148219. (C) The intensity of the differential expression of the overlapped DEGs between cBAVs and cTAVs. (D) Volcano plot of the DEGs between women and men with CAVD (from GSE102249). (E) The intensity of the differential expression of gender-specific DEGs in CAVD.