Table 2.
Outcomes of the primary and secondary indicators
| Indicators | Antibiotic group | Surgery group | RR (95% CI) | z | p |
|---|---|---|---|---|---|
| Cure rate of complication-free treatment at 1 year | 69.4%(468/674) | 88.8%(609/686) | 0.81(0.73–0.91) | 3.65 | 0.000 < 0.05 |
| Total complications | 3.9%(50/1270) | 9.5%(119/1257) | 0.43(0.31–0.58) | 5.36 | 0.000 < 0.05 |
| 4.8%(30/631) | 14.5%(91/626)a | 0.34(0.23–0.49) | 5.55 | 0.000 < 0.05 | |
| 3.1%(20/639) | 4.4%(28/631)b | 0.72(0.41–1.24) | 1.19 | 0.236 | |
| Complications after appendectomy | 9.5%(119/1257) | 11.9%(47/394) | 1.38(0.70–2.73) | 0.93 | 0.353 |
| Therate of complicated appendicitis formed after treatments | 5%(63/1264) | 9.9%(128/1289) | 0.71(0.36–1.42) | 0.96 | 0.338 |
| The rate of appendectomy with non-appendicitis | 4.2%(30/721) | 3.7%(27/732) | 1.11(0.69–1.79) | 0.43 | 0.670 |
| Length of hospital stay | NA | NA | 0.08(-0.11-0.27)c | 0.80 | 0.422 |
| Quality of life after treatments | NA | NA | 0.09(-0.03-0.20)c | 1.53 | 0.127 |
| The effect of appendicoliths on the effectiveness of antibiotic treatment | 38.1%(101/265)d | 18.9%(140/740)e | 2.94(1.28–6.74) | 2.55 | 0.011 < 0.05 |
NA Not Available
aOpen surgery
bLaparoscopic surgery
cSMD (95%CI)
dThe appendicolith rate of the patients whose symptoms were not improved in the antibiotic treatment group
eThe appendicolith rate of the patients whose symptoms were improved in the antibiotic treatment group