Table 6.
Healthcare visits among ACH cases vs controls, overall and by age (CPRD HES-linked cohort)
| Healthcare visit type | Age group (years) | Mean number of visits per person per year (SD) | p-value | Mean length of inpatient stay, days (SD) | ||
|---|---|---|---|---|---|---|
| Cases (N = 275) | Controls (N = 1052) | Cases (N = 275) | Controls (N = 1052) | |||
| GP Consultations | Overall | 8.02 (7.99) | 5.10 (4.96) | p < 0.0001* | N/A | |
| 0–10 | 5.35 (6.98) | 3.47 (3.49) | p < 0.005* | |||
| 11–17 | 12.83 (6.61) | 1.00 (1.54) | p < 0.005* | |||
| 18–59 | 6.60 (7.02) | 3.96 (4.18) | p < 0.0001* | |||
| ≥ 60 | 8.23 (7.84) | 6.37 (6.29) | p < 0.005* | |||
| Hospital outpatient visits | Overall | 3.02 (3.56) | 1.37 (1.87) | p < 0.0001* | N/A | |
| 0–10 | 3.52 (3.59) | 0.83 (1.40) | p < 0.0001* | |||
| 11–17 | 1.71 (1.65) | 0.40 (0.73) | p < 0.0001* | |||
| 18–59 | 1.67 (1.83) | 1.07 (1.42) | p < 0.0001* | |||
| ≥ 60 | 2.53 (5.25) | 1.83 (2.29) | p = 0.1464 | |||
| Hospital in-patient admissions | Overall | 0.51 (0.77) | 0.26 (0.35) | p < 0.0001* | 4.13 (13.16) | 2.30 (6.54) |
| 0–10 | 0.72 (1.17) | 0.23 (0.40) | p < 0.0001* | 1.68 (6.03) | 1.40 (3.57) | |
| 11–17 | 0.18 (0.16) | 0.10 (0.17) | p < 0.005* | 3.28 (10.98) | 1.65 (6.25) | |
| 18–59 | 0.25 (0.25) | 0.19 (0.21) | p < 0.005* | 5.01 (16.02) | 1.63 (4.56) | |
| ≥ 60 | 0.63 (0.78) | 0.36 (0.43) | p < 0.005* | 6.45 (14.73) | 3.91 (9.49) | |
ACH Achondroplasia; CPRD Clinical Practice Research Database; ER Event rate; GP General practitioner; N/A Not applicable; PY Person years; RR Rate ratio; SD Standard deviation
*Statistically significant result (α = 0.05)