Table 3.

Correlation between inflammatory cytokine concentrations and clinical symptoms in case group

a, Correlation between inflammatory cytokines and PANSS scores and subscales in patients
	Tie-2		IL-1β	IL-4	Positive		Negative		General	Total
	r		P. adj	r	P. adj		r		P. adj	r		P. adj		r		P. adj	r			P. adj	r
Tie-2	1.000
IL-1β	-0.326*		-	1.000
IL-4	-0.292		-	0.183	-		1.000
Positive	0.026		0.873	0.373*	0.075		-0.006		0.971	1.000
Negative	0.040		0.809	0.045	0.784		-0.078		0.633	-0.025		-		1.000
General	0.097		0.550	-0.010	0.953		0.007		0.968	0.220		-		0.417**		-	1.000
Total	0.069		0.971	0.278	0.082		-0.057		0.971	0.574**		-		0.615**		-	0.754**			-	1.000
b, Correlation between inflammatory cytokines and BPRS scores and subscales in patients
	Tie-2		IL-1β		IL-4		Affect			Positive	Negative			Resistance			Activation				Total
	r	P. adj	R	P. adj	r	P. adj	r	P. adj		r	P. adj		r	P. adj	r		P. adj	r	P. adj		r
Tie-2	1.000
IL-1β	-.326*	-	1.000
IL-4	-0.292	-	0.183	-	1.000
Affect	-0.201	0.307	0.142	0.475	-0.146	0.473	1.000
Positive	-0.224	0.246	0.300	0.136	-0.012	0.943	0.397*	-		1.000
Negative	-0.074	0.707	0.279	0.153	0.095	0.651	0.169	-		0.248	-		1.000
Resistance	-0.102	0.635	0.365*	0.061	-0.089	0.656	0.286	-		0.519**	-		0.421**	-	1.000
Activation	-0.258	0.186	0.226	0.246	-0.033	0.871	0.576**	-		0.263	-		0.314*	-	0.565**		-	1.000
Total	-0.300	0.136	0.417**	0.027	-0.032	0.871	0.560**	-		0.714**	-		0.581**	-	0.840**		-	0.739**	-		1.000

Note: Tie-2 Tyrosine kinase receptor with immunoglobulin and epidermal growth factor homology domain 2, IL-1β Interleukin-1β, IL-4 Interleukin-4

^*p ≤ 0.05

^**p ≤ 0.001, P.adj: adjusted P-values