Fig. 4.

LVC and NTG both decreased propagation of CSD while NTG also increased CSD susceptibility. LVC or NTG administration did not affect CSD A amplitudes, B durations, D frequency and E velocity. C LVC did not change CSD thresholds, whereas NTG-injected rats had lower thresholds. F LVC increased propagation failure as compared to CTRL group. Data were shown as mean ± SEM. Statistical analysis was performed with one-way ANOVA and posthoc Tukey’s test or Kruskal Wallis test and posthoc Dunn’s multiple comparisons test (* < 0,05; ** < 0,01) (n = 4–5/group)