Fig. 7.

Effects of SE on the expression of proteins related to oxidative stress and apoptosis in skeletal muscle of db/db mice. The protein expression of (a) 4-HNE, (b) cytoplasmic HO-1, (c) cytoplasmic SOD, (d) cytoplasmic GPx, and (e) cytoplasmic Bax/Bcl-2 ratio. All results were expressed following normalization with α-tubulin. The data were presented as mean ± SD. N + : db/m +  + saline; NC: db/db + saline; PC: db/db + metformin; SE200: db/db + stevia extract 200 mg/kg BW; SE500: db/db + stevia extract 500 mg/kg BW; SV: db/db + stevioside 40 mg/kg BW. ^### p < 0.001, ^## p < 0.01, ^# p < 0.05 vs. N + ; ^*** p < 0.001, ^** p < 0.01, ^* p < 0.05 vs. NC