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. 2023 Jul 24;16:249. doi: 10.1186/s13071-023-05853-7

Table 1.

Kasokero virus (KASV) infection and shedding dynamics in KASV-inoculated bats versus KASV + tick salivary gland extract (SGE)-inoculated bats

Parameter KASV-inoculated bats, arithmetic mean (SD)a KASV + tick SGE-inoculated bats, arithmetic mean (SD)a Statistical hypothesis testing
Duration of viremia (days) 7.7 (1.9) 6.9 (0.7) Welch’s t-test, Welch-corrected t = 1.127, df = 7.572, P = 0.2941
Peak viremia loads (log10TCID50eq/ml) 5.4 (0.4)a 4.9 (0.3)a Mann-Whitney U = 7, P = 0.0262*
Cumulative viremia loads (log10TCID50eq/ml) 5.8 (0.4)a 5.2 (0.3)a Unpaired t-test, t = 2.845, df = 12, P = 0.0148*
Duration of oral shedding (days) 8.6 (1.9) 7.3 (1.7) Unpaired t-test, t = 1.332, df = 12, P = 0.2077
Peak oral shedding loads (log10TCID50eq/ml) 4.0 (1.0)a 3.5 (1.1)a Unpaired t-test, t = 0.7603, df = 12, P = 0.4617
Cumulative oral shedding loads (log10TCID50eq/ml) 4.2 (0.9)a 3.8 (0.9)a Unpaired t-test, t = 0.9088, df = 12, P = 0.3813
Duration of rectal shedding (days) 4.9 (2.5) 2.6 (1.3) Unpaired t-test, t = 2.571, df = 12, P = 0.0507
Peak rectal shedding loads (log10TCID50eq/ml) 3.0 (0.6)a 2.1 (0.5)a Unpaired t-test, t = 2.926, df = 12, P = 0.0127*
Cumulative rectal shedding loads (log10TCID50eq/ml) 3.2 (0.6)a 2.3 (0.5)a Unpaired t-test, t = 3.299, df = 12, P = 0.0064*
Detection ratio in urine (detections/collections) 0.48 (0.17) 0.44 (0.12) Unpaired t-test, t = 0.4967, df = 12, P = 0.6284

aIf KASV- and KASV + tick SGE-inoculated bat datasets were lognormally distributed, geometric means and geometric standard deviations were calculated, and statistical hypothesis testing was performed on log-transformed datasets; otherwise, arithmetic means and standard deviations were calculated, and no data transformations were performed prior to statistical hypothesis testing. SD: standard deviation, log10TCID50eq/ml: log10 50% tissue culture infectious dose equivalents per ml; t: test statistic, df: degrees of freedom, and P: probability