Table 1.
The top four associated SNPs
| Chr | SNP | BP position | Risk allele /Protective allele | Risk allele frequency affected | Risk allele frequency unaffected | OR | 95% CI | P-value (MLMA) | Absolute effect size (BayesR) |
|---|---|---|---|---|---|---|---|---|---|
| 1 | BICF2P714726 | 73,777,342 | G /A | 0.94 | 0.85 | 2.66 | 1.84—3.85 | 1.90 × 10–06 | 0.017 |
| 18 | BICF2P1386405 | 27,949,474 | T/C | 0.34 | 0.20 | 2.03 | 1.60—2.57 | 9.42 × 10–06 | 0.007 |
| 32 | BICF2G630590287 | 17,605,832 | T/C | 0.33 | 0.21 | 1.84 | 1.46—2.33 | 1.21 × 10–05 | 0.003 |
| 34 | BICF2S232639 | 14,960,862 | G/A | 0.54 | 0.38 | 1.92 | 1.55—2.36 | 6.77 × 10–06 | 0.010 |
The four top SNPs identified in the association analysis in the MLMA in GCTA, and with the effect size from BayesR. The base pair position is given in can.fam4 reference genome. The association study was based on 731 phenotyped SBTs (407 controls and 324 cases), and 94,697 autosomal SNP markers