Fig. 6.

circ-NFKB1 acts as a sponge for miR-374a-3p. A Venn diagram depicting overlapping miRNAs across the three databases. B RT-qPCR was conducted to detect the relative expression of miR-203a-5p in IL-β-induced chondrocytes. C Relative expression of miR-203a-5p in sham and OA cartilage tissue. D The miR-203a-5p expression in miR-203a-5p mimic or miR-203a-5p inhibitor groups. E The predicted binding sites between miR-203a-5p and NFKB1 and luciferase reporter assay results. F The interaction between NFKB1 and miR-203a-5p was confirmed by RIP assay. *P < 0.05