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. 2023 Jul 25;18:528. doi: 10.1186/s13018-023-03990-4

Fig. 8.

Fig. 8

Overexpression of ERBB4 could partially reverse the inhibitory effects of circ-NFKB1 knockdown by siRNA of circ-NFKB1 on IL-1β induced chondrocytes apoptosis. A The overexpression efficiency of ERBB4 was determined by RT-qPCR. B Flow cytometry was applied to measure the apoptosis ratio in transfected chondrocytes. C Caspase-3, Bax and Bcl-2 protein expressed that detected by western blot analysis. D The concentration of inflammatory cytokines was measured by ELISA in transfected chondrocytes. *P < 0.05