Table 2.

Assay results of MET, EMP, and LIN in their pharmaceutical tablets using the proposed MEKC method

	MEKC Method			Reference Method*
	MET	EMP	LIN	MET	EMP	LIN
MET/EMP/LIN (Mixture I)a Mean % recovery ± SD RSD % Er % t e F e	100.27 ± 0.16 0.16 0.27 1.71 1.12	99.84 ± 0.68 0.68 −0.16 0.53 3.04	100.44 ± 0.71 0.71 0.44 2.22 3.91	99.96 ± 0.025 0.025 −0.04	99.65 ± 0.39 0.39 −0.35	99.65 ± 0.36 0.36 −0.35
MET/EMP (Mixture II)b Mean % recovery ± SD RSD % Er % t e F e	100.04 ± 0.59 0.59 0.04 0.80 5.15	99.60 ± 0.68 0.68 −0.40 2.10 4.00		99.81 ± 0.26 0.26 −0.19	98.88 ± 0.34 0.34 −1.12
MET/LIN (Mixture III)c Mean % recovery ± SD RSD % Er % t e F e	100.52 ± 1.50 1.49 0.52 0.12 5.01		100.46 ± 1.96 1.95 0.46 0.07 1.85	100.17 ± 0.67 0.67 0.17		100.54 ± 1.44 1.43 0.54
EMP/LIN (Mixture IV)d Mean % recovery ± SD RSD % Er % t e F e		99.84 ± 0.80 0.80 −0.16 2.24 1.91	101.10 ± 0.75 0.74 1.10 2.15 3.16		100.83 ± 0.58 0.57 0.83	100.28 ± 0.42 0.42 0.28

*The reference methods used were HPLC methods for Mix I (7) and Mix II (13), CE for Mix III (22) and spectrophotometric method for Mix IV (21)

^aLabeled to contain 12.5 EMP, 2.5 LIN and 500 METµg.mL⁻¹

^bLabeled to contain 12.5 EMP and 500 MET µg. mL⁻¹

^cLabeled to contain 2.5 LIN and 500 MET µg. mL⁻

^dLabeled to contain 25 LIN and 50 EMP µg. mL⁻

^eTheoretical values at 95% confidence level (n = 5) for t and F are 2.31 and 6.39, respectively