Table 1.
Clinical characteristics of the subjects
NOA | OA | P value | |
---|---|---|---|
No. of patients (n) | 25 | 14 | |
Age (y) | 49 ± 10.5 | 54.43 ± 10.77 | 0.133 |
Female sex (%) | 64 | 64.3 | 0.224 |
BMI | 21.43 ± 1.71 | 30.35 ± 1.83 | < 0.0001 |
Atopy (%) | 36 | 28.58 | 0.289 |
FEV1 (%) | 80.84 ± 20.7 | 73.76 ± 18.7 | 0.299 |
FEV1/FVC | 81.72 ± 15.92 | 79.77 ± 15.58 | 0.715 |
Smoking history (never/smoker), no. (%) | 76/24 | 71.4/28.6 | 0.522 |
ACT | 16.92 ± 3.89 | 18.14 ± 4.66 | 0.386 |
Sputum Neu (%) | 29.27 ± 20.91 | 56.55 ± 28.58 | 0.0048 |
Sputum Eso (%) | 16.20 [5.97, 31.35] | 16.4 ± 14.29 | 0.418 |
Peripheral blood | |||
WBC (× 10^9/L) | 6.16 ± 1.51 | 6.48 ± 2.34 | 0.603 |
Neutrophils (%) | 48.87 ± 16.25 | 50.49 ± 14.31 | 0.759 |
Eosinophils (%) | 4.5 ± 4.78 | 3.79 ± 2.57 | 0.607 |
Categorical variables are represented as n (%), and continuous variables following a normal distribution are represented as the mean ± SD, and continuous variables with non-normal distribution are represented as median and quartile. NOA: nonobese asthma; OA: obese asthma; BMI: body mass index; FEV1: forced exhaled volume at 1 s; FVC: forced vital capacity; ACT: asthma control test; Neu: neutrophils; Eos: eosinophils