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. 2023 Jul 11;11:1198545. doi: 10.3389/fbioe.2023.1198545

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Copyright © 2023 Cui, Wang, Mu, Huang, Wang, Luo and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Establishment exosome sustain-released system with fibrin on Ta surface. (A) the morphology of exosomes on Ta surface observed by SEM; (B) the exosomes adsorption on Ta surface with different exosome concentration; (C) the morphology of fibrin on Ta surface observed by SEM; (D) the uptake of exosome (green) by BMSCs(blue) observed by LCSM; (E) the semi-quantitative analysis of exosomes in BMSCs; (F) the morphology of fibrin and exosome on Ta surface observed by SEM; (G) the exosome release on Ta surface with fibrin. (a. p < 0.05, compare with 0; b. p < 0.05, compare with 0.1 μg/μL; c. p < 0.05, compare with 0.5 μg/μL; ns. no significances).