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Expression status of CTLA-4 in different autoimmune diseases.
| Disease | Expression Status | References |
|---|---|---|
| Rheumatoid arthritis (RA) | PBMC, spleen, lymph node ↓ | (90, 91) |
| Systemic lupus erythematosus (SLE) | PBMC ↓ | (92–94) |
| Multiple sclerosis (MS) | PBMC, spleen, lymph node ↓ | (95, 96) |
| Type 1 diabetes (T1D) | Spleen and thymus cell↓ | (97, 98) |
| Autoimmune thyroid disease (AITD) | Spleen and lymph node↓ | (99–101) |
| Myasthenia gravis (MG) | PBMC↓ | (102) |
↓ denotes the downregulation or lower expression.
