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. Author manuscript; available in PMC: 2023 Jul 25.
Published in final edited form as: N Engl J Med. 2022 Feb 26;386(16):1505–1518. doi: 10.1056/NEJMoa2118813

Figure 2. Mean Changes from Baseline in Asthma-Related Scores.

Figure 2.

The least-squares mean differences between treatment groups in the changes from baseline in asthma-related scores were calculated with the use of a mixed model. The Asthma Control Test (Panel A) is a participant-administered tool for assessing the level of asthma control. Total scores range from 5 to 25, with a score of 20 to 25 indicating well-controlled asthma, a score of 16 to 19 indicating asthma that was not well controlled, and a score of 5 to 15 indicating very poorly controlled asthma; the minimal clinically important difference is 3 points. The Asthma Symptom Utility Index (Panel B) is a participant-administered tool for assessing preference-based quality of life. The summary score is on a continuous scale, ranging from 0 (worst possible symptoms) to 1 (no symptoms); the minimal clinically important difference is 0.09. I bars indicate 95% confidence intervals. The widths of the confidence intervals have not been adjusted for multiplicity and cannot be used to infer treatment effects.