Table 1.

The Polish drug program criteria and the Polish Neurological Society criteria for second-line treatment (B.46 drug program) for patients treated with first-line treatment (B.29 drug program). To qualify for the second-line treatment, patients must meet both of these conditions

	Polish drug program criteria	Polish Neurological Society criteria
Relapses	At least two moderate episodes requiring steroid treatment during a minimum 1-year treatment cycle or One severe relapse after 6 months of treatment	At least one relapse with an increase of EDSS ≥ 1 point
MRI lesions	At least two Gd+ lesions or At least three new T2 lesions	At least one new T1 lesion (Gd+) or Two new T2 lesions (a total of at least nine lesions)
Timeframe	The previous 12 months	The previous 12 months

EDSS – Expanded Disability Status Scale, Gd+ – gadolinium-enhancing lesion