Table 2.

Distinctive characteristics of WLPTC compared to other PTC subtypes.

Histological features	Classic PTC	WLPTC	Oncocytic PTC	Tall cell PTC
Growth pattern	Papillary	Papillary	Papillary or follicular	Papillary
Cell apperance	Slighly eosinophilic cytoplasm	Oncocytic changes	Oncocytic changes	Oncocytic changes ; three times as tall as wide
Papillary nuclear features	Yes	Yes	Yes	Mainly elongated dark nuclei
Lymphocytic infiltrate	Slight	Dense	Absent	Slight
Underlying CLT	Possible	Very common	Absent	Rare
Extrathyroid extension	Possible	Rare	Possible	Common
Vasular invasion	Rare	Rare	Possible	Common
LN metastases	Common	Common	Common	Very common
Distant metastases	Possible	Rare	Possible	Common

PTC, Papillary Thyroid Cancer; WLPTC, Warthin-like Papillary Thyroid Cancer; CLT, Chronic Lymphocytic Thyroiditis; LN, Lymph Node.