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Summary of the mechanism by purinergic receptor P2Y12 drives ConA-mediated autoimmune hepatitis through hexokinase 2-dependent glycolysis pathway. Purinergic receptor P2Y12 (P2RY12) affects T cells HK2 stability through regulating PI3K/Akt signaling pathway and inhibiting lysosomal degradation in ConA-mediated autoimmune hepatitis.
