Table 1.
Correlation between DBF4 expression and clinicopathologic variables in 107 HCC patients.
| Clinicopathological characteristics | All subjects (n = 107) | DBF4 low expression (n = 54) | DBF4 high expression (n = 53) | P | |
|---|---|---|---|---|---|
| Age (years) | 54.6 ± 12.7 | 53.3 ± 13.5 | 56.0 ± 11.8 | 0.27 | |
| Gender | Male | 100 (93.5%) | 50 (92.6%) | 50 (94.7%) | 0.72 |
| Female | 7 (6.5%) | 4 (7.4%) | 3 (5.7%) | ||
| HBV infection | With | 88 (82.2%) | 43 (79.6%) | 45 (84.9%) | 0.48 |
| Without | 19 (17.8%) | 11 (20.4%) | 8 (15.1%) | ||
| Underlying cirrhosis | Present | 87 (81.3%) | 46 (85.2%) | 41 (77.4%) | 0.30 |
| Absent | 20 (18.7%) | 8 (14.8%) | 12 (22.6%) | ||
| Serum AFP level | ≤400 ng/mL | 67 (62.6%) | 31 (57.4%) | 36 (67.9%) | 0.26 |
| >400 ng/mL | 40 (37.4%) | 23 (42.6%) | 17 (32.1%) | ||
| No. of nodules | Solitary | 87 (81.3%) | 45 (83.3%) | 42 (79.2%) | 0.59 |
| Multiple | 20 (18.7%) | 9 (16.7%) | 11 (20.8%) | ||
| Tumor size | ≤5cm | 32 (29.9%) | 22 (40.7%) | 10 (18.9%) | 0.13 |
| >5cm | 75 (70.1%) | 32 (59.3%) | 43 (81.1%) | ||
| Tumor differentiation | Grading I-II | 76 (71.0%) | 38 (70.4%) | 38 (71.7%) | 0.88 |
| Grading II-IV | 31 (29.0%) | 16 (29.6%) | 15 (29.0%) | ||
| Microvascular invasion | Present | 42 (39.3%) | 20 (37%) | 22 (41.5%) | 0.64 |
| Absent | 65 (60.7%) | 34 (63.0%) | 31 (58.5%) | ||