Figure 8.
The combination immunotherapy based on astragaloside III and photodynamic therapy (PDT) for the treatment of colon cancer. (A) Schematic illustration of synergistic immunotherapy mediated by the astragaloside III activated NK cells and the PDT activated T cells. (B) The combination therapy significantly reduced the tumor size and weight of CT26-tumor bearing mice. (C) The combined treatment showed improved ROS generation effect in CT26 cells. The synergistic immunotherapy promoted (D) NK cell activation and (E) CT26 cell inhibition effect. Reproduced from 159 with permission from Elsevier.