Table 2.
Prognosis factors of complete remission in patients with MN receiving rituximab based on the results of univariate Cox proportional hazard analysis.
HR | HR (95% CI) | p Value | |
---|---|---|---|
Gender | 1.364 | (0.434–4.289) | 0.596 |
Age (per year) | 1.011 | (0.975–1.049) | 0.547 |
Duration (per month) | 0.994 | (0.979–1.009) | 0.415 |
BMI (per 1 kg/m2) | 1.192 | (0.969–1.465) | 0.096 |
Smoker | 0.958 | (0.271–3.444) | 0.958 |
Drinker | 1.391 | (0.311–6.182) | 0.664 |
MAP (per 1 mmHg) | 1.059 | (0.996–1.127) | 0.067 |
Hypertension | 2.307 | (0.733–7.262) | 0.153 |
Diabetes | 0.288 | (0.064–1.284) | 0.103 |
eGFR (per 1 mL/min/1.73 m2) | 1.040 | (1.001–1.041) | 0.040* |
URBC (per 1/µL) | 1.005 | (0.997–1.014) | 0.176 |
Hb (per 1 g/L) | 1.031 | (0.995–1.069) | 0.086 |
Alb (per 1 g/L) | 1.021 | (0.955–1.091) | 0.542 |
ALT (per 1 IU/L) | 1.026 | (0.990–1.063) | 0.153 |
TC (per 1 mmol/L) | 0.953 | (0.760–1.194) | 0.675 |
TG (per 1 mmol/L) | 0.915 | (0.683–1.224) | 0.549 |
Upro (per 1 grade) | 0.873 | (0.441–1.729) | 0.697 |
CRP (per 1 mg/L) | 0.938 | (0.806–1.090) | 0.403 |
BMI: body mass index; MAP: mean arterial pressure; eGFR: estimated glomerular filtration rate; URBC: urine red blood cell; Hb: hemoglobin; Alb: albumin; ALT: alanine transaminase; Upro: urine protein; TG: triglyceride; TC: total cholesterol; CRP: c-reactive protein; 95% CI: 95% confidence interval; HR: hazard ratio
Proteinuria was divided into three grades, less than 4 g is grade 1, 4–8 g is grade 2, and greater than 8 g is grade 3.
p < 0.05 was considered statistically significant.