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RNA-seq analysis Identifies gene expression profile regulated by COS. (A) Heatmap shows differential gene expression profiles, with upregulation in red, downregulation in blue. (B) Gene ontology (GO) function analysis histogram. BP is marked by dark cyan, CC is marked by sienna and MF is marked by steel blue. The bar chart was constructed through the bioinformatics platform. (C) mRNA expression of Pam16, Trem2 and Esrra relative to GAPDH (mean ± SEM, *p < 0.05, n = 8).
