Table 3.

Included studies, demographics, and results.

						AE N and rates detected by the GTT
Ref.no.	First author	Speciality	Quality score	Sample size of the GTT—number of medical records reviewed	Number of admissions	AEs (N)	Per 1000 patient days	AEs per 100 admissions	% of admissions with an AE	% of AEs detected using the GTT that were also detected in the corresponding IRSs
[21]	Agarwal	Paediatric intensive care unit (PICU)	29	734		1488	286a	203b	62	4
[22]	Hooper	Paediatric intensive care unit (PICU)	23	59		98	599a	166b	56	2
[23]	Kennerly	General inpatients	28		9017	3430	61	38	32	3.5
[24]	Mull	General inpatients	28	273	288	109	52	38	21	0.9
[30]	Naessens	General inpatients	23		235	65	–	28b	28	14
[25]	Najjar	General inpatients	28	640		91	–	14b	14	4.4
[10]	Nilsson	Intensive care unit (ICU)	25	128		41	–	32	20	2.4
[31]	Reilly	Inpatient psychiatric	31	8005		583	–	7b	–	37.4
[26]	Rutberg	General inpatients	26	960		271	33	28b	21	6.3
[32]	Samal	Inpatient oncology	22	88		79	–	90b	–	2.5
[27]	Sharek	Neonatal intensive care unit (NICU)	28	749		554	32	74b	–	8
[28]	Stockwell	Paediatric	26	600		240	55	40	24	9.2
[29]	Takata	Paediatric	30	960		107	16	11	7	3.7
[17]	Tchijevitch	Unplanned transfer to ICU or death	27	141		10c	–	7b	7c	0

^a Reported as 100 patient days in original papers (calculated to 1000 patient days).

^b Calculated by authors of this paper.

^c Fatal and life threatening ADEs only.