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. Author manuscript; available in PMC: 2024 May 20.
Published in final edited form as: Lancet. 2023 Apr 20;401(10389):1669–1680. doi: 10.1016/S0140-6736(23)00811-5

Table 1.

Baseline characteristics of eligible children enrolled in the study by RSV infection status in infancy. *

Baseline characteristic All (n=1,946) RSV infection in infancy (n=1,741)*

No (n=797) Yes (n=944) p-value§



Age at enrollment (days) 55 (16–78) 51 (15–75) 60 (17–86) 0.005
Female sex 926 (48%) 391 (49%) 436 (46%) 0.23
Race and ethnicity 0.004
  Black non-Hispanic 343 (18%) 116 (15%) 192 (20%)
  White non-Hispanic 1,267 (65%) 551 (69%) 580 (61%)
  Hispanic 170 (9%) 65 (8%) 91(10%)
  Other 166 (9%) 65 (8%) 81 (9%)
RSV season 0.81
  2012–2013 858 (44%) 340 (43%) 408 (43%)
  2013–2014 1,088 (56%) 457 (57%) 536 (57%)
Birth month <0.001
  June 270 (14%) 90 (11%) 161 (17%)
  July 313 (16%) 103 (13%) 179 (19%)
  August 329 (17%) 141 (18%) 153 (16%)
  September 261 (13%) 120 (15%) 120 (13%)
  October 269 (14%) 123 (15%) 106 (11%)
  November 251 (13%) 114 (14%) 106 (11%)
  December 253 (13%) 106 (13%) 119 (13%)
Gestational age (weeks) 39 (39–40) 39 (39–40) 39 (39–40) 0.12
Birth weight (grams) 3,405 (3,120–3,740) 3,405 (3,120–3,717) 3,433 (3,121–3,749) 0.28
Birth by cesarean section 611 (31%) 233 (29%) 325 (34%) 0.02
Ever breastfeeding 1,528 (81%) 653 (82%) 730 (78%) 0.07
Daycare attendance in infancy 590 (34%) 234 (29%) 344 (38%) <0.001
Presence of another child aged <6 years at home during infancy 983 (51%) 353 (44%) 523 (55%) <0.001
Exposure to secondhand smoking in utero or in early infancy 425 (22%) 162 (20%) 193 (20%) 0.94
Maternal asthma 379 (19%) 160 (20%) 182 (19%) 0.67
Type of insurance 0.13
  Federal or state 1,055 (54%) 402 (50%) 521 (55%)
  Private 867 (45%) 384 (48%) 411 (44%)
  Other or Unknown 24 (2%) 11 (1%) 11 (1%)

Definition of abbreviations: RSV = Respiratory syncytial virus.

*

Data presented as median (interquartile range) for continuous variables or number (%) for categorical variables.

Data calculated for children with complete data.

Of the 1,946 eligible children enrolled in the study, 1,741 (88%) had available data to be classified into one of the two groups.

§

The p-values for the comparison between the groups using a Mann-Whitney U or chi-squared test are shown.