Figure 2.
ZFP57 promotes the proliferation and inhibits apoptosis of ovarian cancer cells. A. Protein expression of ZFP57 in five OC cell lines. Interference efficiency verification of ZFP57 in CAOV3 and OV429 cells. Overexpression efficiency verification of ZFP57 in OVCAR3 and OVCAR8 cells. B. Relative cell viability of CAOV3 and OV429 cells expressing NC or Si-ZFP57. C. Relative cell viability of OVCAR3 and OVCAR8 expressing lenti-vector or lenti-ZFP57. D-E. Clone formation experiments of CAOV3 and OV429 cells expressing NC or Si-ZFP57 and OVCAR3 and OVCAR8 cells expressing lenti-vector or lenti-ZFP57. F-G. Flow cytometry for detection of apoptosis by Annexin/PI double staining in CAOV3 and OV429 cells expressing NC or Si-ZFP57 and OVCAR3 and OVCAR8 cells expressing lenti-vector or lenti-ZFP57. Data are presented as means ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001, ****P < 0.0001.
