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. 2023 Jul 9;14(11):2039–2050. doi: 10.7150/jca.84601

Figure 4.

Figure 4

ZFP57 affects G1 phase arrest in OC cells. A. Top 20 KEGG pathways of target genes on the data from RNA-seq. B. Heat map of cell cycle related genes using our RNA-Seq data. C. The mRNA expression of CDC7, CCNE2 and CCNA2 in CAOV3 and OV429 cells expressing siNC and siZFP57. D. Cell cycle was detected by FACS analysis in CAOV3 and OV429 cells expressing NC or Si-ZFP57, representative pictures on the top and percent of phase on the button. E. Cell cycle was detected by FACS analysis in OVCAR3 and OVCAR8 expressing lenti-vector or lenti-ZFP57, representative pictures on the top and percent of phase on the button. Data are presented as means ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001, ****P < 0.0001.