Table 2.

Significant factors included in the multivariate analyses for 1,665 nasopharyngeal carcinoma patients at stage N1-3

Endpoint	Variable	HR	95% CI	P Value
PFS	Age	1.210	1.001-1.463	0.049
	Pathological subtype	2.000	1.245-3.214	0.004
	T category	1.808	1.460-2.238	<0.001
	N category	1.525	1.252-1.857	<0.001
	Lymph node necrosis	1.643	1.353-1.994	<0.001
	Chemotherapy	1.314	0.959-1.800	0.089
OS	Sex	1.473	1.111-1.955	0.007
	Age	1.584	1.255-1.999	<0.001
	Pathological subtype	1.973	1.104-3.529	0.022
	T category	2.079	1.595-2.711	<0.001
	N category	1.794	1.421-2.265	<0.001
	Lymph node necrosis	1.609	1.275-2.030	<0.001
	Chemotherapy	1.520	1.060-2.180	0.023
DMFS	Pathological subtype	1.743	0.925-3.286	0.086
	T category	1.764	1.322-2.355	<0.001
	N category	2.052	1.583-2.661	<0.001
	Lymph node necrosis	1.634	1.260-2.118	<0.001
LRRFS	Pathological subtype	1.896	0.889-4.046	0.098
	T category	1.859	1.334-2.591	<0.001
	Lymph node necrosis	1.706	1.275-2.283	<0.001

Note 1: Hazard ratios and P-values were calculated by using the Cox proportional hazards model.

Abbreviations: HR, hazard ratio; CI, confidence interval; PFS, progress-free survival; OS, overall survival; DMFS, distant metastasis-free survival; LRRFS, locoregional relapse-free survival.