Table 1.
Bacterial RNAs whose lifetime is controlled by a riboswitch
| lysC | yitJ | glmS | P1-Vc2 | sugE | |
|---|---|---|---|---|---|
| Species | E. coli | B. subtilis | B. subtilis | V. cholerae | L. pneumophila |
| Riboswitch | Lysine | SAM-I (S-box) | GlmS | c-di-GMP-I | Guanidine-III |
| Ligand | Lysine | S-adenosylmethionine | Glucosamine-6-phosphate | Cyclic di-GMP | Guanidine |
| Effect of ligand binding | Destabilization | Destabilization | Destabilization | Protection | Protection |
| Cleavage activity affected | RNase E | RNase Y | GlmS ribozyme | 3′ exonucleases | RNase E |
| Role of the ligand | Allosteric | Allosteric | Catalytic | Allosteric | Allosteric |