Fig. 3. Representative confocal laser scanning microscopy (CLSM) images and analysis of cellular uptake of nanoparticles in hEM15A endometrial cell line in vitro. (a) hEM15A cells incubated with NaGdF4@PEG@bevacizumab–Cy5.5 nanoparticles (NPBCNs) (upper) and NaGdF4@PEG–NHS–Cy5.5 nanoparticles (NPCNs) (middle). After blocking the VEGF signaling pathway with free bevacizumab, hEM15A cells were incubated with NPBCNs (bottom). (b) Quantitative analysis of mean fluorescence intensity in hEM15A cells. ****, p < 0.001; ns, non-significant.
