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Fig. 5. Histological assessment of endometriosis lesion in the targeted group. (a) Representative histologic image (400×) from of models with endometriosis. (b) Representative colocalization images of endometriosis lesions from rats injected with NaGdF4@PEG@bevacizumab–Cy5.5 nanoparticles (NPBCNs). Cy5.5 channel: NPBCNs; Hoechst channel: cell nuclei and FITC channel: the immunofluorescence staining for the makers for ectopic endometrial cells [cyclooxygenase-2 (COX2) oxytocin receptor (OTR), nerve growth factor (NGF) and PGP9.5].