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. Author manuscript; available in PMC: 2024 Jul 19.
Published in final edited form as: Cell Syst. 2023 Jul 19;14(7):605–619.e7. doi: 10.1016/j.cels.2023.06.003

Figure 7: BayesTME reveals gradual tumor invasion and confirms interface programs in a second zebrafish melanoma model.

Figure 7:

A. Histology of the zebrafish B sample; cutout: tumor interface with the gradual invasion of tumor cells into the muscle region; bottom: corresponding tumor-muscle interface with tumor/non-tumor proportions capturing the gradient of tumor invasion present in histology. B-C. BayesTME discovers 10 cell types with their proportions and biologically plausible marker genes. D. 16 spatial transcriptional programs discovered at a 5% FDR.