Table 1.
Summary of reported characteristics of oral CTCL
Number of cases with oral MF | 76 |
Sex (n = 65) | Total (%) |
Male | 40 (62) |
Female | 25 (38) |
Male:female | 1.6:1 |
Race, n | |
Caucasian | 17 |
African American | 2 |
Other | 1 |
Unknown | 56 |
Age (n = 64) | |
Mean in years (range) | 57.8 (12–85) |
CTCL type | Total (%) |
MF | 57 (75) |
CD4+CD8+ | 8 (10) |
Transformed MF | 6 (8) |
Sézary Syndrome | 3 (4) |
CD4−CD8− | 2 (3) |
Areas of involvement, n | |
Tongue | 37 |
Palate | 35 |
Gingiva | 19 |
Buccal mucosa | 16 |
Tonsils | 12 |
Pharynx | 10 |
Esophagus | 9 |
Larynx | 7 |
Trachea | 5 |
Uvula | 4 |
Vestibule | 2 |
Alveolar ridge | 2 |
Primary lesion morphology, n | |
Tumor | 23 |
Plaque | 17 |
Nodule | 8 |
Papule | 1 |
Secondary lesion characteristics, n | |
Erythema | 17 |
Ulcer | 25 |
Firm | 9 |
Edema | 7 |
Erosion | 6 |
Pseudomembrane | 5 |
Necrosis | 4 |
Soft/boggy | 4 |
Leukoplakia | 3 |
Perforation | 1 |
Mobile | 1 |
Gangrenous | 1 |
Eruption | 1 |
Fungating | 1 |
Associated symptoms, n | |
Dysphagia | 14 |
Pain | 11 |
Glossitis | 7 |
Odynophagia | 5 |
Hoarseness | 1 |
Asymptomatic | 2 |
Burning sensation | 2 |
Painless | 2 |
Difficulty in speaking | 1 |
Nasal regurgitation | 1 |
Length of time for oral CTCL to present from initial cutaneous lesions (n = 52) | |
Mean in years (range) | 6.4 years |
Range | 2 months −30 years |
Outcome (n = 51) | Total (%) |
Death | 34 (67) |
Alive | 17 (33) |
Causes of death (n = 33) | Total (%) |
Sepsis | 14 (42) |
Advanced disease | 11 (33) |
Unknown | 5 (15) |
Other | 3 (9) |
Length of time from initial oral lesion to death (n = 30) | |
Mean in months (range) | 13.2 (0.5–48) |
MF, mycosis fungoides.