Table 3.
Univariate Analysis of Characteristics of 54 Dead Patients with Candida BSI
| Factors | Survival n = 109 | Death n = 54 | χ2 | P |
|---|---|---|---|---|
| Age≥60 years old (IQR) | 57 (52.29) | 35 (64.81) | 2.303 | 0.129 |
| Sex (male/female) | 60/49 | 34/20 | 0.927 | 0.336 |
| LOS (days) | 38.52±44.68 | 27.30±18.12 | 2.749 | 0.097 |
| Hypertension | 30 (27.52) | 22 (40.74) | 2.904 | 0.088 |
| Diabetes | 20 (18.35) | 16 (29.63) | 2.671 | 0.102 |
| Hematological malignancy | 23 (21.10) | 2 (3.70) | 8.417 | 0.004* |
| Solid-organ cancer | 29 (26.61) | 9 (16.67) | 1.995 | 0.158 |
| Lung infection | 62 (56.88) | 38 (70.37) | 2.771 | 0.096 |
| Heart disease | 35 (32.11) | 17 (31.48) | 0.007 | 0.935 |
| Nervous system disease | 36 (33.03) | 17 (31.48) | 0.039 | 0.843 |
| Digestive system disease | 35 (32.11) | 25 (46.30) | 3.124 | 0.077 |
| Chronic kidney disease | 33 (30.28) | 14 (25.92) | 0.333 | 0.564 |
| Chronic liver disease | 28 (25.69) | 16 (29.63) | 0.285 | 0.594 |
| Urinary catheter | 59 (54.13) | 44 (81.48) | 11.615 | <0.001* |
| Stomach tube | 32 (29.36) | 29 (53.70) | 9.140 | 0.003* |
| Body cavity drainage tube | 33 (30.28) | 25 (46.30) | 4.044 | 0.044* |
| Arteriovenous catheters | 32 (29.36) | 37 (68.52) | 22.685 | <0.001* |
| Mechanical ventilation | 44 (40.37) | 41 (75.93) | 18.298 | <0.001* |
| Tracheotomy | 25 (22.94) | 16 (29.63) | 0.859 | 0.354 |
| Hemodialysis | 3 (2.75) | 11 (20.37) | 16.904 | <0.001* |
| Immunosuppressant use | 77 (70.64) | 41 (75.93) | 0.504 | 0.478 |
| ICU admission | 38 (34.86) | 36 (66.67) | 14.735 | <0.001* |
| History of department transfer | 19 (17.43) | 8 (14.81) | 0.179 | 0.672 |
| Previous surgery | 48 (44.04) | 23 (42.59) | 0.031 | 0.861 |
| Combined with other fungal infection | 9 (8.26) | 12 (22.22) | 6.275 | 0.012* |
| Combined with other bacterial infection | 73 (66.97) | 34 (62.96) | 0.257 | 0.612 |
| APACHE II score | 12.72±6.14 | 18.85±6.30 | 5.945 | <0.001* |
| Neutrophil count | 7.72±8.08 | 11.08±12.39 | 4.681 | 0.030* |
| Hemoglobin | 106.27±25.25 | 102.69±27.40 | 18.980 | <0.001* |
| Platelet count | 179.50±112.82 | 167.61±108.79 | 0.319 | 0.572 |
| CRP | 73.40±80.12 | 106.95±85.13 | 0.933 | 0.334 |
| Procalcitonin | 9.41±20.81 | 13.70±29.00 | 1.257 | 0.262 |
| 1, 3-β-D-glucan | 231.58±246.09 | 375.49±250.11 | 3.600 | 0.058 |
Note: *Significant statistical difference (P<0.05).
Abbreviations: IQR, interquartile range; BSI, bloodstream infection; LOS, length of stay; ICU, intensive care unit; CRP, C-reactive protein; χ2, chi-square value; P, significance.