Table 3.
Demographics and Clinical Characteristics of Hospitalized Patients with Omicron Variant
| Variables | Omicron-Type Strains | ||
|---|---|---|---|
| Mild and moderate (n=285) | Severe and critical (n=116) | P-value | |
| Age, years | 65.00 (54.00, 77.00) | 73.24 (14.14) | 0.000 |
| <20 | 1 (0.4%)# | 0 (0.0%)# | |
| ≥20, <60 | 107 (37.5%)* | 19 (16.4%)* | |
| ≥60 | 177 (62.1%)* | 97 (83.6%)* | |
| Male sex | 144 (50.5%) | 74 (63.8%) | 0.016 |
| BMI, kg/m2 | 24.30 (21.70, 26.86) | 24.30 (24.30, 24.30) | 0.513 |
| ≤25 | 182 (63.9%)* | 94 (81.0%)* | |
| >25 | 103 (36.1%)* | 22 (19.0%)* | |
| Signs and symptoms at admission | |||
| Cough | 284 (99.6%) | 116 (100%) | 0.523 |
| Fever | 237 (83.2%) | 105 (90.5%) | 0.059 |
| Duration of fever, d | 3.00 (2.00, 5.00) | 5.00 (3.00, 8.00) | 0.000 |
| Temperature, °C | 38.50 (38.00, 39.00) | 38.60 (38.00, 39.00) | 0.103 |
| Sputum | 284 (99.6%) | 116 (100%) | 0.523 |
| Shortness of breath | 208 (73.2%) | 111 (95.7%) | 0.000 |
| Chest pain | 17 (6.0%) | 8 (6.9%) | 0.726 |
| Sore throat | 51 (17.9%) | 16 (13.8%) | 0.318 |
| Diarrhea | 24 (8.4%) | 15 (12.9%) | 0.167 |
| Nausea and vomiting | 120 (42.1%) | 42 (36.2%) | 0.275 |
| Muscle ache | 155 (54.4%) | 58 (50.0%) | 0.425 |
| Respiratory rate | 20.00 (18.00, 20.00) | 23.00 (21.00, 25.00) | 0.000 |
| ≤20 | 227 (79.6%)* | 23 (19.8%)* | |
| >20 | 58 (20.4%)* | 93 (80.2%)* | |
| Fingertip oxygen saturation, % | 98.00 (96.00, 98.00) | 92.00 (88.00, 94.50) | 0.000 |
| Bacterial co-infection | 8 (2.8%) | 15 (12.9%) | 0.000 |
| Comorbidity | |||
| Any | 236 (82.8%) | 104 (89.7%) | 0.083 |
| Cardiovascular diseases | 123 (43.2%) | 66 (56.9%) | 0.012 |
| Diabetes | 56 (19.6%) | 31 (27.6%) | 0.119 |
| Digestive diseases | 24 (8.5%) | 8 (6.9%) | 0.603 |
| Respiratory diseases | 83 (29.1%) | 27 (23.3%) | 0.234 |
| Central nervous system diseases | 29 (10.2%) | 26 (22.4%) | 0.001 |
| Hematological diseases | 2 (0.7%) | 1 (0.9%) | 0.866 |
| Immune diseases | 13 (4.6%) | 8(6.9%) | 0.341 |
| Urinary diseases | 14 (4.9%) | 5 (4.3%) | 0.797 |
| Cancer | 22 (7.7%) | 7 (6.0%) | 0.555 |
| Treatment | |||
| Oxygen therapy | 171 (60.0%)* | 114 (98.3%)* | 0.000 |
| Nasal catheter to snuff oxygen | 168 (58.9%)* | 18 (15.5%)* | |
| Mechanical ventilation | 3 (1.1%)* | 96 (82.8%)* | |
| Non-invasive | 3 (1.1%)* | 67 (57.8%)* | |
| Invasive | 0 (0.0%)* | 29 (25.0%)* | |
| Glucocorticoids | 117 (41.1%) | 87 (75.0%) | 0.000 |
| Days from first admission to discharge | 7.00 (6.00, 9.00) | 11.70 (5.60) | 0.000 |
Notes: Data are presented as number (%) or means (standard deviation) or median (interquartile range). P values indicate differences between mild/moderate type and severe/critical type. *In the same row indicate significant differences between mild/moderate type and severe/critical type. #In the same row indicate no differences between mild/moderate type and severe/critical type.