Table 5.

Results of univariate survival analysis using log rank test for other clinicopathologic parameters.

	OS	DSS	RFS
Clinical parameters
Age (continuous)	0.006	NS	NS
Sex	NS	NS	NS
Post-operative radiation therapy	NS	NS	NS
Post-operative chemotherapy	0.019	0.048	0.004
Characteristics of primary tumors
AJCC pT stage/tumor size categorical)	NS	0.008	0.003
Tumor size (continuous)	0.024	0.002	0.004
Lymphovascular invasion	NS	NS	NS
Perineural invasion	<0.001	0.029	0.033
Margin status	NS	NS	NS
Characteristics of nodal metastasis
AJCC pN stage	<0.002	0.001	0.004
Size of largest involved lymph node (continuous)	NS	NS	NS
Size of largest metastasis continuous)	NS	NS	NS
Laterality of positive lymph node	NS	NS	0.011
Number of positive lymph nodes	<0.001	0.002	0.012
Rounded/well-circumscribed soft tissue deposit	NS	NS	NS
Subgroups of cases with ENE
Vertical extent of ENE continuous)	NS	0.049	NS
Horizontal extent of ENE continuous)	NS	NS	NS
Size of lymph node with most ENE ((continuous)	NS	NS	0.034
Size ratio of metastasis/involved lymph node in the lymph node with the most ENE (continuous)	NS	NS	NS
Number of positive lymph nodes with ENE	0.003	0.020	NS
Tissue involved by ENE	0.019	0.002	0.040
Desmoplastic reaction in ENE	NS	NS	NS
Irregular soft tissue deposit	<0.001	<0.001	<0.001

NS non-significant.

Values are P values obtained using log rank test for categorical variables and cox proportional hazards model for continuous variables.