Figure 2.

Illustration of how the ORs for developing POD change with age, duration of surgery and intraoperative blood pressure management. Color coding is similar to Figure 1. The illustration of the four-factor multivariable model includes a box for each of four representative age groups. The z-axis represents an increasing duration of surgery, and x-/y-axes depict intraoperative changes of systolic blood pressure (sBP) compared with baseline values before surgery (25th percentile, i.e. lowest proportion, and 90th percentile, i.e. highest proportion, of intraoperative sBP changes). ORs for an episode increase with age and duration of surgery in line with Figure 1. The model based on this study’s data reveals that either lowering or increasing intraoperative sBP beyond baseline sBP values increases the risk for POD, i.e. blood pressure management should be even more meticulously taken care of in older patients undergoing longer surgery. BP indicates blood pressure.