TABLE 1.
Summary of the Recruitment Process and Visit Plan
| Enrolment | Study period | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| preoperative (V0) | intraoperative (V1) | Postoperative (V2.1, V2.2, etc.) | 3-mo follow-up (V3) | 1-yr follow-up (V4) | ||||||
| Time point | −7d±7 | 0 | 1d | 2d | 3d | 4d | etc. | 90d±14 | 360d±14 | |
| Eligibility screen | X | — | — | — | — | — | — | — | — | — |
| Informed consent | X | — | — | — | — | — | — | — | — | — |
| Demographic data | — | X | — | — | — | — | — | — | — | — |
| Medical history | — | X | — | — | — | — | — | — | X | X |
| Cognitive testing | — | X | — | — | — | — | — | — | X | X |
| Activities of daily living | X | — | — | — | — | — | — | X | — | |
| Frailty | — | X | — | — | — | — | — | — | — | — |
| Quality of life | — | X | — | — | — | — | — | — | X | — |
| Vital parameters | — | — | X | — | — | — | — | — | — | — |
| Delirium screening | — | X | — | X | X | X | X* | X* | — | — |
| Medication | — | X | X | X | X | X | X* | X* | X | X |
| Pain | — | X | — | X | X | X | X* | X* | — | — |
| Mobilization | — | — | — | X | X | X | X* | X* | — | — |
Study visits V0-V4 had to be completed by all participants. V2 included compulsory examinations for the first three days, which were discontinued if the patients did not develop POD.17
*
Examinations were otherwise continued until POD ended or the patient was discharged.