Table 2.

Skin Thickness, Surface Area, and EI Parameters at Baseline and after 4, 8, and 12 Weeks

Group	Control Group (n = 13)				CGF Group (n = 13)				P (CON vs. CGF)
	Mean/Median	SEM/IQR	P (Visit vs. V1)		Mean/Median	SEM/IQR	P (Visit vs. V1)
Skin thickness, mm
V1	1.6	0.1	—	—	1.5	0.1	—	—	0.987	ns
V2	1.4	0.1	<0.001	b	1.6	0.1	0.711	ns	0.569	ns
V3	1.1	0.1	<0.001	b	1.4	0.1	0.167	Ns	0.047	a
V4	1.0	0.1	<0.001	b	1.3	0.1	0.023	a	0.047	a
Epidermal thickness, mm
V1	0.3	0.0	—	—	0.3	0.0	—	—	>0.999	ns
V2	0.3	0.0	0.716	ns	0.3	0.0	0.069	ns	0.792	ns
V3	0.2	0.0	0.129	ns	0.3	0.0	0.035	a	0.935	ns
V4	0.2	0.0	0.016	a	0.2	0.0	0.047	a	0.287	ns
Dermal thickness, mm
V1	1.3	0.1	—	—	1.3	0.1	—	—	0.984	ns
V2	1.1	0.1	<0.001	b	1.3	0.1	0.497	ns	0.400	ns
V3	0.9	0.1	<0.001	b	1.2	0.1	0.294	ns	0.045	a
V4	0.8	0.1	<0.001	b	1.1	0.1	0.079	ns	0.041	a
Surface area
V1	198.0	59.5–578.6	—	—	149.5	48.6–268.7	—	—	0.281	ns
V4	280.3	111.4–670.5	0.001	b	258.0	187.7–465.7	<0.001	b	0.614	ns
Increment of surface area
V4–V1	77.7	18.5	—	—	135.0	15.7	—	—	0.027	a
EI
V1	1.5	0.2	—	—	1.2	0.1	—	—	0.107	ns
V4	2.4	0.1	<0.001	b	2.6	0.1	<0.001	b	0.449	ns
Increment of EI
V4–V1	0.9	0.1	—	—	1.4	0.2	—	—	0.030	a

IQR, interquartile range; V1, visit 1 (baseline); V2, visit 2 (4 weeks); ns, not significant (P > 0.05); V3, visit 3 (8 weeks); V4, visit 4 (12 weeks).

^aP < 0.05.

^bP < 0.01.