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| Exclusion Criteria |
|---|
| • Age < 18 years • sCr baseline < 0.5 mg/dL |
| • Patients with AKI (stage 2/3 KDIGO) diagnosis or in renal replacement treatment within the first 12 hours of ICU stay • Patients with missing values for more than 4 consecutive hours of urine output and heart rate and MAP data more than 4 days of laboratory measurements data |
