TABLE 4.
Summary of tumor growth inhibition of compound F8, F8·2HCl and apatinib.
| Compound | Administration | Dose (mg/kg) | Inhibition (%) | |
|---|---|---|---|---|
| Schedule | Route | |||
| F8 | p.o. | bid | 75.0 | 52.8 |
| Apatinib | p.o. | bid | 37.5 | 50.0 |
| F8·2HCl | p.o. | bid | 37.5 | 60.6 |
| p.o. | bid | 75.0 | 70.1 | |
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