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. 2023 Jul 25;2023(7):CD015078. doi: 10.1002/14651858.CD015078

IRCT20180205038626N7.

Study name The investigation of the effectiveness of ASA usage on the incidence of cardiovascular events in patients with coronavirus (COVID‐19) A clinical trial study
Methods
  • Trial design: randomised single‐blinded trial, phase 2

  • Type of publication: trial registry

  • Setting: Razi Hospital, Rasht

  • Recruitment dates: 5 December 2020

  • Country: Iran

  • Language: English

  • Number of centres: NR

  • Inclusion criteria: all patients admitted with a diagnosis of COVID‐19 based on CT scan or PCR; over 18 years

  • Exclusion criteria: patients admitted to the ICU. Patients with a history of ulcers and gastrointestinal problems. Patients receiving aspirin. Patients with a history of thrombotic events such as heart attack or stroke or a history of atrial fibrillation, congestive heart failure, active bleeding or coagulation disorders such as thrombocytopenia.

  • Trial registration number: IRCT20180205038626N7

  • Date of trial registration: 27 December 2020

  • Prospective completion date: not reported

Participants
  • Age: > 18 years

  • Gender: NR

  • Ethnicity: NR

  • Number of participants (recruited/allocated/evaluated): 36/NR/NR

  • Severity of disease: SARS‐CoV‐2 infection (COVID‐19)

  • Additional diagnoses: NR

  • Previous treatments (e.g. experimental drug therapies, oxygen therapy, ventilation): NR

Interventions
  1. Daily aspirin 80 mg for 3 months

  2. Standard treatment for 3 months

  • Concomitant therapy: NR

  • Treatment cross‐overs: NR

  • Duration of follow‐up: NR

  • Treatment cross‐overs: NR

  • Compliance with assigned treatment: NR

Outcomes Primary outcomes
  1. Thromboembolic events

  2. Cardiovascular accidents

  3. Brain accidents


Secondary outcomes
  1. Death


Additional outcomes: NR
Starting date NR
Contact information Contact: Zahra Ahmadnia, +98 13 3361 8177, zahmadnia@gums.ac.ir
Notes
  • Sponsor/funding: Rasht University of Medical Sciences

  • COIs: NR

  • Other: NR