Figure 2. Lifespan trajectories of population-level areal asymmetry.

Homotopic lifespan trajectories of surface area in clusters exhibiting population-level (A) leftward (yellow plots; yellow clusters) and (B) rightward (pink plots; blue clusters) areal asymmetry (mm²). Larger plots on the left show the mean age trajectory across all clusters exhibiting leftward (top) and rightward (bottom) asymmetry. Note that the unit of measurement is the average surface area of a vertex within the cluster. Dark colours correspond to LH trajectories. All age trajectories were fitted using GAMMs. Data is residualized for sex, scanner and random subject intercepts. Clusters are numbered for reference. As outliers were removed on a region-wise basis (Methods), the number of observations underlying the plots range from 7862 to 7874 (see Supplementary file 1E).